Ferries from Saint Efstratios to Mytilini can peak at up to undefined daily sailings, Sailing frequency typically peaks in the summer months, with approximately undefined departures offered each week. While schedules may be reduced from Saint Efstratios to Mytilini in other seasons, ferry services are often still available.

Ferry travel from Saint Efstratios to Mytilini on average typically takes -. The earliest ferry usually leaves from Saint Efstratios at -, arriving to Mytilini at - The latest ferry departs at - and arrives at -.