Ferries from Lipsoi to Kalymnos can peak at up to 2 daily sailings, Sailing frequency typically peaks in the summer months, with approximately 9 departures offered each week. While schedules may be reduced from Lipsoi to Kalymnos in other seasons, ferry services are often still available.

Ferry travel from Lipsoi to Kalymnos on average typically takes 1h 20m. The earliest ferry usually leaves from Lipsoi at 10:05, arriving to Kalymnos at 01:20 The latest ferry departs at 23:45 and arrives at 15:25.