Ferries from Lipsoi to Leros can peak at up to 2 daily sailings, Sailing frequency typically peaks in the summer months, with approximately 9 departures offered each week. While schedules may be reduced from Lipsoi to Leros in other seasons, ferry services are often still available.

Ferry travel from Lipsoi to Leros on average typically takes 30m. The earliest ferry usually leaves from Lipsoi at 10:05, arriving to Leros at 00:10 The latest ferry departs at 23:30 and arrives at 14:35.