Ferries from Mytilini to Saint Efstratios can peak at up to undefined daily sailings, Sailing frequency typically peaks in the summer months, with approximately undefined departures offered each week. While schedules may be reduced from Mytilini to Saint Efstratios in other seasons, ferry services are often still available.

Ferry travel from Mytilini to Saint Efstratios on average typically takes -. The earliest ferry usually leaves from Mytilini at -, arriving to Saint Efstratios at - The latest ferry departs at - and arrives at -.