Ferries from Patmos to Mytilini can peak at up to undefined daily sailings, Sailing frequency typically peaks in the summer months, with approximately undefined departures offered each week. While schedules may be reduced from Patmos to Mytilini in other seasons, ferry services are often still available.

Ferry travel from Patmos to Mytilini on average typically takes -. The earliest ferry usually leaves from Patmos at -, arriving to Mytilini at - The latest ferry departs at - and arrives at -.