Ferries from Santa Cruz to Huelva can peak at up to 2 daily sailings, Sailing frequency typically peaks in the summer months, with approximately 7 departures offered each week. While schedules may be reduced from Santa Cruz to Huelva in other seasons, ferry services are often still available.

Ferry travel from Santa Cruz to Huelva on average typically takes 38h 60m. The earliest ferry usually leaves from Santa Cruz at 01:30, arriving to Huelva at 06:30 The latest ferry departs at 20:30 and arrives at 08:00.