Ferries from Santorini to Heraclio can peak at up to 2 daily sailings, Sailing frequency typically peaks in the summer months, with approximately 9 departures offered each week. While schedules may be reduced from Santorini to Heraclio in other seasons, ferry services are often still available.

Ferry travel from Santorini to Heraclio on average typically takes 1h 40m. The earliest ferry usually leaves from Santorini at 06:45, arriving to Heraclio at 04:30 The latest ferry departs at 23:50 and arrives at 19:15.