Ferries from Santorini to Serifos can peak at up to 2 daily sailings, Sailing frequency typically peaks in the summer months, with approximately 7 departures offered each week. While schedules may be reduced from Santorini to Serifos in other seasons, ferry services are often still available.

Ferry travel from Santorini to Serifos on average typically takes 3h 25m. The earliest ferry usually leaves from Santorini at 08:00, arriving to Serifos at 13:40 The latest ferry departs at 15:05 and arrives at 18:40.