Ferries from Thessaloniki to Patmos can peak at up to undefined daily sailings, Sailing frequency typically peaks in the summer months, with approximately undefined departures offered each week. While schedules may be reduced from Thessaloniki to Patmos in other seasons, ferry services are often still available.

Ferry travel from Thessaloniki to Patmos on average typically takes -. The earliest ferry usually leaves from Thessaloniki at -, arriving to Patmos at - The latest ferry departs at - and arrives at -.